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June 30, 2022

Vascudyne Receives BioBusiness Award from Regenerative Medicine Minnesota for Treatment of Nerve Injury

Vascudyne is proud to announce a grant award from Regenerative Medicine Minnesota for the development of a peripheral nerve wrap using regenerative engineering tissue tube. The one-year, $100,000 grant will advance the development of peripheral nerve protection devices to address the unmet clinical needs of patients with chronic debilitating nerve injury such as carpal tunnel syndrome.

Chronic nerve compression remains one of the most common forms of peripheral nerve injury. For example, carpal tunnel syndrome incidence may be as high as 10% of the general population and leads to 400,000-500,000 carpal tunnel release procedures each year in the US. Poor outcomes with carpal tunnel release include scar tissue formation within and/or around the nerve and adhesions between the nerve and surrounding tissues. Native tissues such as adipose tissue and veins have been used as protective barriers but have been associated with shortcomings such as donor site morbidity, limited availability of healthy autologous tissue, and surgical complications.

Vascudyne’s engineered tissue can be manufactured as a durable graft to support nerves and serve as a barrier between the healing nerve and surrounding tissue. Nerve grafts with variable diameters and lengths can be produced as needed to match the anatomy of the commonly injured nerves, such as brachial plexus, radial nerve, ulnar nerve, and median nerve.

Nerve protection, repair, and regeneration remains an unmet clinical need, and Vascudyne’s engineered tissue technology that is 100% biological with regenerative potential offers a promising solution.

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These are investigational uses that have not been approved by any health authority. Safety and efficacy have not been established and there is no guarantee that pipeline products or investigational uses will receive approval from health authorities.

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